Rintis is a leading researcher in the study of malaria with expertise in pathogenesis, genomics, cell biology, and gene expression studies of malaria parasites.
In the absence of persistence infection, antibody to malaria antigens are lost, suggesting a defect in B-cell memory induction. The specific targets of immunity remain unknown, especially those that are correlated with protection to malaria. The B- and T-cells responses to malaria will be studied in clinical samples from Indonesia.
Why Rintis decided to enter the fellowship:
There is a strong partnership that has been built between my laboratory, the Eijkman Institute, and my Australian colleagues. This relationship has involved establishing a longitudinal study in malaria-infected individuals in Indonesia last year. We attempted to explore immunological determinants associated with protection of malaria through more advanced research conducted in leading Australian institutions.
Rintis’s impressive past achievements:
Rintis is currently Principal Investigator, Head of Malaria Pathogenesis Laboratory Unit, the Eijkman Institute for Molecular Biology in Jakarta, Indonesia.
Since 2011, she has been involved in research advancing malaria vaccine development under the coordination of the Ministry of Research and Technology in the Republic of Indonesia. She was also a member of Expert Panels of Laboratory Working Group, the National Commission for Malaria Eradication as part of the Ministry of Health.
Rintis graduated with a PhD in Molecular Biology of Malaria Parasites from the University of Melbourne in Australia and has spent her working life researching in this field. She has headed many investigations and received prestigious awards and internationally competitive grants including the L'Oreal for Women in Science Fellowship. This fellowship was auspiced by the L'Oreal-UNESCO Special Programme for Research and Training in Tropical Diseases which is hosted by the World Health Organization (WHO) and the Asia Pacific Malaria Elimination (APMEN), where Rintis studied the genetic diversity of malaria parasites in Indonesia. She has also received support from the Malaria Transmission Consortium-UNICEF, funded by the Bill and Melinda Gates Foundation to develop a plasmodium database in Indonesia.
Rintis obtained a grant to study the angiogenic proteins expression in severe malaria through the Scientific Program of Indonesia-the Netherlands (SPIN/KNAW) where she undertook several research projects in Holland. She has also taken part inresearch in Australia as a postdoc through the Endeavour Postdoctoral Research Fellowships. Rintis has participated and presented her research results in numerous workshops and meetings held overseas including in India, Thailand, the Netherlands, Korea, Spain, Singapore, Kenya, Australia, and the UK. Rintis has published her research findings in 14 peer-reviewed journals in malaria-related fields.