STAFF PROFILE
Professor Jiming Ye
Position:
Honorary Professor
College / Portfolio:
STEM College
Phone:
+61399257419
Email:
jiming.ye@rmit.edu.au
Campus:
City Campus
Contact me about:
Research supervision
- Overexpression of Nedd42 for the treatment of insulin resistance induced by high fructose diet. Funded by: Diabetes Australia Research Trust Grant 2016 from (2016 to 2017)
- The Combined Use of Proteomics and Small Molecules for Target Identification and Pathway Analysis. Funded by: ARC Discovery 2011 from (2011 to 2014)
- Pathways to Diabetes Prevention. Administered by Garvan Institute of Medical Research.. Funded by: National Health and Medical Research Council (NHMRC) Project Grant Pre-2014 from (2010 to 2013)
- Investigation of novel triterpenoids as new potent AMPK activators for the treatment of insulin resistant states.. Funded by: National Health and Medical Research Council (NHMRC) Project Grant Pre-2014 from (2010 to 2012)
15 PhD Completions
Drug discovery for diabetes, molecular pharmacology and target identification. Research projects include lipid synthesis, ER-stress and insulin resistance in cells and animal models.
- Ou, Y.,You, Z.,Yao, M.,Ye, J., et al, . (2023). Naproxen-Derived New Compound Inhibits the NF-?B, MAPK and PI3K/Akt Signaling Pathways Synergistically with Resveratrol in RAW264.7 Cells In: Molecules, 28, 1 - 13
- Li, C.,Xu, Y.,Hu, Y.,Zhou, X.,Huang, Z.,Ye, J.,Rao, Y. (2022). Matrine counteracts obesity in mice via inducing adipose thermogenesis by activating HSF1/PGC-1a axis In: Pharmacological Research, 177, 1 - 13
- Rao, Y.,Kuang, Z.,Li, C.,Ye, et al, J. (2021). Gut Akkermansia muciniphila ameliorates metabolic dysfunction-associated fatty liver disease by regulating the metabolism of L-aspartate via gut-liver axis In: Gut Microbes, 13, 1 - 19
- Fouda, S.,Khan, A.,Chan, S.,Mahzari, A.,Zhou, X.,Qin, C.,Vlahos, R.,Ye, J. (2021). Exposure to cigarette smoke precipitates simple hepatosteatosis to NASH in high-fat diet fed mice by inducing oxidative stress In: Clinical science, 135, 2103 - 2119
- Rao, Y.,Xu, Z.,Hu, Y.,Ye, J., et al, . (2020). Discovery of a promising agent IQZ23 for the treatment of obesity and related metabolic disorders In: European Journal of Medicinal Chemistry, 192, 1 - 21
- Khan, A.,Fouda, S.,Mahzari, A.,Chan, S.,Zhou, X.,Ratnam, C.,Vlahos, R.,Ye, J. (2020). Cigarette smoking blocks the benefit from reduced weight gain for insulin action by shifting lipids deposition to muscle In: Clinical Science, 134, 1659 - 1673
- Zhou, X.,Fouda, S.,Li, D.,Zhang, K.,Ye, J. (2020). Involvement of the autophagy-er stress axis in high fat/carbohydrate diet-induced nonalcoholic fatty liver disease In: Nutrients, 12, 1 - 12
- Rao, Y.,Lu, Y.,Li, C.,Ye, J., et al, . (2019). Bouchardatine analogue alleviates non-alcoholic hepatic fatty liver disease/non-alcoholic steatohepatitis in high-fat fed mice by inhibiting ATP synthase activity In: British Journal of Pharmacology, 176, 2877 - 2893
- Mahzari, A.,Li, S.,Zhou, X.,Li, D.,Fouda, S.,Alhomrani, M.,Alzahrani, W.,Robinson, S.,Ye, J. (2019). Matrine protects against MCD-induced development of NASH via upregulating Hsp72 and downregulating mTOR in a manner distinctive from metformin In: Frontiers in Pharmacology, 10, 1 - 2
- Zhou, X.,Fouda, S.,Zeng, X.,Li, D.,Zhang, K.,Xu, J.,Ye, J. (2019). Characterization of the therapeutic profile of albiflorin for the metabolic syndrome In: Frontiers in Pharmacology, 10, 1 - 13