2019
Malik S, Spencer SJ. Early life stress and metabolism. Current Opinion in Behavioral Sciences. Accepted Jan 2019.
Sominsky L, Goularte JF, Andrews ZB, and Spencer SJ. Acylated ghrelin supports the ovarian transcriptome and follicles in the mouse: implications for fertility. Frontiers in Endocrinology. Accepted Jan 2019.
De Luca SN, Sominsky L, Soch A, Wang H, Ziko I, Rank MM, and Spencer SJ. Conditional microglial depletion in rats leads to reversible anorexia and weight loss by disrupting gustatory circuitry. Brain Behavior and Immunity. Accepted December 2018.
2018
Spencer SJ, Basri B, Sominsky L, Soch A, Ayala MT, Reineck P, Gibson BC, and Barrientos R. High fat diet worsens the impact of ageing on microglial function and morphology in a region-specific manner. Neurobiology of Aging. 74:121-134 (2018).
Ziko I, Sominsky L, De Luca SN, Lelngei F, and Spencer SJ. Acylated ghrelin suppresses the cytokine response to lipopolysaccharide and does so independently of the hypothalamic-pituitary-adrenal axis. Brain Behavior and Immunity. 74:86-95 (2018).
Wang H, Blackall M, Sominsky L, Spencer SJ, Vlahos R, Churchill M, and Bozinovski S. Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess Serum Amyloid A production. Journal of Neuroinflammation. 15(1):200 (2018).
Sominsky L, Jasoni JL, Twigg HR, and Spencer SJ. Hormonal and nutritional regulation of postnatal hypothalamic development. Journal of Endocrinology. 237(2):R47-64 (2018).
Sominsky L, Ong LK, Ziko Z, Dickson PW, and Spencer SJ. Early life diet increases capacity for catecholamine biosynthesis from the adrenal gland acutely and long-term in the rat. Molecular and Cellular Endocrinology. 15(470):295-303 (2018).
Sominsky L, De Luca SN, and Spencer SJ. Microglia: key players in neurodevelopment and neuronal plasticity. International Journal of Biochemistry & Cell Biology. 1(94):56-60 (2018).
2017
Spencer SJ, Korosi A, Layé S, Shukitt-Hale B, and Barrientos RM. Food for thought: how diet influences cognitive function and emotion. NPJ Science of Food. 7 (2017).
Baker KD, Loughman A, Spencer SJ, and Reichelt AC. The impact of obesity and hypercaloric diet consumption on anxiety and emotional behavior across the lifespan. Neuroscience & Biobehavioral Reviews. 18(83):173-182 (2017).
De Luca SN, Ziko I, Dhuna K, Sominsky L, Tolcos M, Stokes L, and Spencer SJ. Neonatal overfeeding by small-litter rearing sensitizes hippocampal microglial responses to immune challenge: reversal with neonatal minocycline and saline injection. Journal of Neuroendocrinology. 9(11):1-14 (2017).
Ziko I, Sominsky L, Nguyen TX, Yam KY, De Luca SN, Korosi A, and Spencer SJ. Hyperleptinemia in neonatally overfed female rats does not dysregulate feeding circuitry. Frontiers in Endocrinology. 8(287):1-11 (2017).
Sominsky L, Hodgson D, McLaughlin EA, Smith R, Wall HM, and Spencer SJ. Linking stress and infertility: a novel role for ghrelin. Endocrine Reviews. 38(5):432-467 (2017).
Yam KY, Ruigrok SR, Ziko I, De Luca S, Lucassen PJ, Spencer SJ*, and Korosi A*. Ghrelin and hypothalamic neuropeptide Y / agouti-related peptide expression are sex-specifically affected by chronic early-life stress exposure in young mice. Psychoneuroendocrinology. 86:73-77 (2017). * Equal co-authors.
Spencer SJ, D’Angelo H, Soch A, Watkins LR, Maier SF, and Barrientos RM. High-fat diet and aging interact to produce neuroinflammation and impair hippocampal- and amygdalar-dependent memory. Neurobiology of Aging. 58:88-101 (2017).
Sominsky L, Ziko I, Nguyen TX, and Spencer SJ. Hypothalamic effects of neonatal diet: reversible and only partially leptin-dependent. Journal of Endocrinology. 234:41-56 (2017).
Tolcos M, Petratos S, Hirst JJ, Wong F, Spencer SJ, Azhan A, Emery B, and Walker DW. Blocked, delayed, or obstructed: What causes poor white matter development in preterm or intrauterine growth restricted infants? Progress in Neurobiology. 154:62-67 (2017).
Sominsky L, Ziko I, and Spencer SJ. Neonatal overfeeding disrupts pituitary signalling in female rats long-term; implications for the stress response. PLoS One. 12(3):e0173498 (2017).
Nguyen JCD, Ali SF, Kosari S, Woodman O, Spencer SJ, Killcross S, and Jenkins TA. Western diet chow consumption in rats induces striatal neuronal activation while reducing dopamine levels without affecting spatial memory in the radial arm maze. Frontiers in Behavioral Neuroscience. 11(22):1-10 (2017).
Sominsky L*, Ziko I*, Nguyen TX, Andrews ZB, and Spencer SJ. Early life disruption to the ghrelin system with over-eating is resolved in adulthood. Neuropharmacology. 113(Pt A):21-30 (2017). * Equal co-authors.
2016
De Luca SN, Sominsky L, Spencer SJ. Delayed spatial win shift on the radial arm maze. Bio-Protocol. 6(23) DOI:10.21769/BioProtoc.2053 (2016).
Stark R, Santos VV, Geenen B, Cabral A, Dinan T, Bayliss JA, Lockie SH, Reichenbach A, Lemus MB, Perello M, Spencer SJ, Kozicz T, and Andrews ZB. Des-acyl ghrelin and ghrelin O-acyltransferase regulate hypothalamic-pituitary-adrenal axis activation and anxiety in response to acute restraint stress in male mice. Endocrinology. 157(10):3945-57 (2016).
Soch A, Bradburn S, Sominsky L, De Luca SN, Murgatroyd C, and Spencer SJ. Effects of exercise on adolescent and adult hypothalamic and hippocampal neuroinflammation. Hippocampus. 26(11):1435-46 (2016).
De Luca SN, Ziko I, Sominsky L, Nguyen CD, Dinan T, Miller AA, Jenkins TA, and Spencer SJ. Early life overfeeding impairs spatial memory performance by reducing microglial sensitivity to learning. Journal of Neuroinflammation. 13:112 (2016).
Sominsky L, Ziko I, Soch A, Smith JT, and Spencer SJ. Neonatal overfeeding induces early decline of the ovarian reserve: implications for the role of leptin. Molecular and Cellular Endocrinology. 431:24-35 (2016).
Ku JM, Taher M, Chin KY, Barsby T, Austin V, Wong CHY, Andrews ZB, Spencer SJ and Miller AA. Protective actions of des-acylated ghrelin on brain injury and blood-brain barrier disruption after stroke in mice. Clinical Science. 130(17):1545-58 (2016).
Cai G, Ziko I, Barwood JM, Soch A, Sominsky L, Molero J, and Spencer SJ. Overfeeding during a critical postnatal period exacerbates hypothalamic-pituitary-adrenal axis responses to immune challenge: a role for adrenal melanocortin 2 receptors. Scientific Reports. 12;6:21097 (2016).
