Dr Charlotte Conn investigates the use of lipid nanomaterials to increase the stability and activity of biopharmaceuticals over prolonged storage and during in-vivo delivery.
therapeutic proteins and peptides; lipid self-assembly materials; nanomaterials; high-throughput design; synchrotron small angle x-ray scattering
Dr Conn’s research focuses on the high-throughput design and structural characterization of new lipidic materials for protein encapsulation. In particular, she investigates the use of lipid nanomaterials to increase the stability and activity of biopharmaceuticals over prolonged storage, and during in vivo delivery.
An improved understanding of the fundamental interactions between proteins and lipidic materials will guide the development of new biomaterials for vaccines and drug delivery, and improve the efficacy of protein therapeutics, which are the fastest growing segment of the pharmaceutical industry.
Dr Conn joined RMIT as a Senior Research Fellow in 2014 from the CSIRO Materials Science and Engineering, where she led the Amphiphile Self-assembly team. Dr Conn was awarded significant funding from national bodies including the ARC and the Science and Industry Endowment Fund.
Dr Conn collaborates across an international network, including Imperial College London, ETH Zurich and the University of Melbourne. She is an Associate Editor at the Australian Journal of Chemistry, and was the former Chair of a Program Advisory Committee at the Australian Synchrotron.
Dr Conn was awarded a Vice-Chancellor’s Senior Research Fellowship in 2017 and is based in the School of Science.