- Development of therapeutic proteins
- Identifying candidates for poultry vaccines
- Development of vaccines for parasites
- Expression of recombinant proteins in various systems
- Structure and function of proteins
- Recombinant vaccines using commercial Salmonella and Influenza vaccines
In the past five years Professor Smooker has been awarded grants well in excess of $1M to research a variety of projects, focusing on vaccines and the development of therapeutic proteins. These funds have come from the Poultry CRC, ACIAR, the ARC and from industry. These projects have attracted and trained post-doctoral fellows and a number of PhD projects (twelve completions since 2004). Honours students and Master of Biotechnology students undertaking research projects are also trained in the laboratory. Professor Smooker also hosts research scientists on sabbatical leave into the laboratory. The Biotechnology laboratory is a vibrant, multicultural laboratory. If you would like to join, please send him an e-mail. We are looking for excellent students (with the potential to obtain scholarships!).
- Nocturne. Research partnership. Developing recombinant toxin molecules as therapeutic proteins, Commenced 2009.
- BioDiem. Research partnership. Recombinant influenza as a vaccine delivery system. Commenced 2011.
- Tall Bennet. Research partnership. Profiling of yeast additives used in the dairy industry. Commenced 2010.
- Bioproperties. Research partnership/ co-supervision of students. Developing a vaccine against campylobacter. Commenced 2009.
- Orica. Research partnership/ co-supervision of students. Identification of bacteria that degrade explosive residues. Commenced 2009.
- Prince Henry's Institute for Medical Research. Co-supervision of postgraduate students
- Burnett Institute. Co-supervision of postgraduate students
- Institute for Biotechnology, Hanoi, Vietnam. Research partnership.
- Miyagi University, Sendai, Japan. Research partnership, staff and student exchange. Conference chair.
- Monash University. Research partnership.
- Thammasat University, Bangkok, Thailand. Research partnership, student exchange.
- Mahidol University, Bangkok, Thailand. Research partnership, student exchange.
- Ramamalga University, Bangkok, Thailand. Staff training.
- Danish Technical University, Copenhagen, Denmark. Student exchange, research partnership.
- Member of the Scientific Advisory board for a large, multi-country Campylobacter vaccine project, CamVac. This project is headquartered at DTU.
Summary of responsibilities
- Biotechnology Laboratory Head
- Program Leader, Master of Biotechnology
- Core member and research group leader (with Dr Anna Walduck) Health Innovations Research Institute
- School of Applied Sciences Research Strength Leader (Infection and Disease)
- Co-convener, Bundoora Protein group
- International Postgraduate Recruitment
Specialty expertise areas
- Antigen discovery
- Vaccine delivery systems
- Molecular parasitology
- Molecular microbiology
- Protein expression, structure and function
Professor Smooker teaches into a variety of postgraduate and undergraduate programs, and am coordinator of Immunology and Bioinformatics courses. He has also undertaken the provision of short courses both internationally, and hosting international scientists in Australia. Please contact him if your institution is interested in training courses in molecular biology, molecular microbiology, food science, or bioinformatics.
The Master of Biotechnology program that Professor Smooker leads has a large intake of both local and international students; please feel free to contact him for information on the program.
- Bachelor of Science (Honours), Monash University, 1983
- PhD, Monash University, 1988
- Phadungsil, W.,Smooker, P.,Vichasri-Grams, S.,Grams, R. (2016). Characterization of a Fasciola gigantica protein carrying two DM9 domains reveals cellular relocalization property In: Molecular and Biochemical Parasitology, 205, 6 - 15
- Labbunruang, N.,Phadungsil, W.,Tesana, S.,Smooker, P.,Grams, R. (2016). Similarity of a 16.5 kDa tegumental protein of the human liver fluke Opisthorchis viverrini to nematode cytoplasmic motility protein In: Molecular and Biochemical Parasitology, 207, 1 - 19
- Yap, H.,Smooker, P. (2016). Development of experimental vaccines against liver flukes In: Methods in Molecular Biology, 1404, 135 - 151
- Cui, B.,Smooker, P.,Rouch, D.,Deighton, M. (2016). Selection of suitable reference genes for gene expression studies in Staphylococcus capitis during growth under erythromycin stress In: Molecular Genetics and Genomics, 291, 1795 - 1811
- McCabe, M.,Foo, C.,Dinger, M.,Smooker, P.,Stanton, P. (2016). Claudin-11 and occludin are major contributors to Sertoli cell tight junction function, in vitro In: Asian Journal of Andrology, 18, 620 - 626
- Saxena, M.,Smooker, P.,Coloe, P. (2015). Induction of crossover by introduction of aro554:Tn10 into Salmonella chromosome In: Frontiers in Bioscience - Elite, 7E, 423 - 433
- Cui, B.,Smooker, P.,Rouch, D.,Deighton, M. (2015). Effects of erythromycin on the phenotypic and genotypic biofilm expression in two clinical staphylococcus capitis subspecies and a functional analysis of ica proteins in S. capitis In: Journal of Medical Microbiology, 64, 591 - 604
- Siricoon, S.,Vichasri Grams, S.,Lertwongvisarn, K.,Abdullohfakeeyah, M.,Smooker, P.,Grams, R. (2015). Fasciola gigantica cathepsin B5 is an acidic endo- and exopeptidase of the immature and mature parasite In: Biochimie, 119, 6 - 15
- Taki, A.,Smooker, P. (2015). Small wonders-the use of nanoparticles for delivering antigen In: Vaccines, 3, 638 - 661
- Lin, I.,Van, T.,Smooker, P. (2015). Live-attenuated bacterial vectors: Tools for vaccine and therapeutic agent delivery In: Vaccines, 3, 940 - 972
- Development of a live vaccine for gut health in poultry. Funded by: ARC Linkage Grant 2016 from (2016 to 2019)
- Nanocapsules made from pure antigenic protein- evaluation of potential as new-generation vaccines. Funded by: The CASS Foundation Science and Medicine Grants 2014 from (2015 to 2016)
- Bioremediation of contaminated radioactive waste . Funded by: Australia Japan Foundation from (2013 to 2014)
- Radiotherapy dose enhancement by scintillating nanoparticles. Funded by: The CASS Foundation Science and Medicine Grant pre-2014 from (2012 to 2013)
- Pathogen Die Off in Air Dried and Stockpiled Biosolids Harvested from Wastewater Lagoon Processes. Funded by: Smart Water Fund from (2011 to 2013)
26 PhD Completions9 PhD Current Supervisions