STAFF PROFILE
Dr Thomas Angelovich
Position:
Postdoctoral Research Fellow
College / Portfolio:
Biomedical Science Cluster
School / Department:
CIID Research Program
Phone:
99256066
Campus:
Bundoora Campus
Contact me about:
Research supervision
Dr Thomas Angelovich studies the mechanisms which drive inflammatory diseases in HIV-infected individuals and the elderly.
Dr Angelovich researches the mechanisms which drive inflammatory diseases (such as cardiovascular disease and dementia) in HIV-infected individuals and the elderly. By understanding this progression, Dr Angelovich aims to identify targets for therapeutic intervention and to improve health outcomes for HIV-infected individuals.
- Angelovich, T.,Trevillyan, J.,Hoy, J.,Wong, M.,Agius, P.,Hearps, A.,Jaworowski, A. (2020). Monocytes from men living with HIV exhibit heightened atherogenic potential despite long-term viral suppression with antiretroviral therapy In: AIDS, 34, 513 - 518
- Jaworowski, A.,Hearps, A.,Angelovich, T.,Hoy, J. (2019). How Monocytes Contribute to Increased Risk of Atherosclerosis in Virologically-Suppressed HIV-Positive Individuals Receiving Combination Antiretroviral Therapy In: Frontiers in Immunology, 10, 1 - 14
- Bonnard, T.,Jayapadman, A.,Azzahra Putri, J.,Angelovich, T.A. et al, . (2018). Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging In: ACS Nano, 12, 6988 - 6996
- Angelovich, T.,Hearps, A.,Oda, M.,Borja, M.,Huynh, D.,Homann, S.,Jaworowski, A.,Kelesidis, T. (2017). Dysfunctional high-density lipoprotein from HIV+ individuals promotes monocyte-derived foam cell formation in vitro In: AIDS, 31, 2331 - 2336
- Roy, S.,Nguyen, H.,Angelovich, T.,Hearps, A.,Huynh, D.,Jaworowski, A.,Kelesidis, T. (2017). Cell-free biochemical fluorometric enzymatic assay for high-throughput measurement of lipid peroxidation in high density lipoprotein In: Journal of Visualized Experiments, 2017, 1 - 10
- Angelovich, T.,Hearps, A.,Maisa, A.,Kelesidis, T.,Jaworowski, A. (2017). Quantification of monocyte transmigration and foam cell formation from individuals with chronic inflammatory conditions In: Journal of Visualized Experiments, 2017, 1 - 10
- Hearps, A.,Agius, P.,Zhou, J.,et al, .,Chachage, M.,Angelovich, T.,Cameron, P.,Giles, M.,Price, P.,Elliott, J.,, . (2017). Persistence of activated and adaptive-like NK cells in HIV+individuals despite 2 Years of suppressive combination antiretroviral therapy In: Frontiers in Immunology, 8, 1 - 12
- Angelovich, T.,Shi, M.,Zhou, J.,Maisa, A.,Hearps, A.,Jaworowski, A. (2016). Ex vivo foam cell formation is enhanced in monocytes from older individuals by both extrinsic and intrinsic mechanisms In: Experimental Gerontology, 80, 17 - 26
- Saleh, S.,Lu, H.,Evans, V.,Harisson, D.,Zhou, J.,Jaworowski, A.,Sallmann, G.,Cheong, K.,Mota, T.,Tennakoon, S.,Angelovich, T.,Anderson, J.,Andrew Harman, A.,Cunningham, A.,Gray, L.,Churchill, M.,Mak, J.,Drummer, H.,Vatakis, D.,Lewin, S.,Cameron, P. (2016). HIV integration and the establishment of latency in CCL19-treated resting CD4(+) T cells require activation of NF-kappa B In: Retrovirology, 13, 1 - 12
- Maisa, A.,Hearps, A.,Angelovich, T.,Pereira, C.,Zhou, J.,Shi, M.,Palmer, C.,Muller, W.,Crowe, S.,Jaworowski, A. (2015). Monocytes from HIV-infected individuals show impaired cholesterol efflux and increased foam cell formation after transendothelial migration In: AIDS, 29, 1445 - 1457
3 PhD Current Supervisions and 1 Masters by Research Current Supervisions
HIV, ageing, Neuroinflammation, Cardiovascular disease
- Characterising the role of epigenetic marks in driving monocyte-derived foam cell formation associated with atherosclerosis in ageing individuals. Funded by: Rebecca L. Cooper Medical Research Foundation - Competitive from (2020 to 2023)
- Developing novel drug delivery strategies to target myeloid reservoirs of HIV in the brain. Funded by: WMIMR Australian Centre for HIV and Hepatitis Virology Research Grant (ACH2) 2018 onwards from (2020 to 2020)
- Elucidating the mechanisms driving the pathophysiology of HIV-associated neurocognitive disorders. Funded by: NHMRC Project Grants 2018 from (2019 to 2021)
- Defining HIV reservoirs in the central nervous system. Funded by: Jack Brockhoff Foundation Medical Grant 2017 onwards from (2018 to 2021)
- Developing BASEScope: a method to detect replication competent HIV for HIV cure research. Funded by: WMIMR Australian Centre for HIV and Hepatitis Virology Research Grant (ACH2) 2018 onwards from (2018 to 2019)