STAFF PROFILE
Dr Thomas Angelovich
Position:
Lecturer
College / Portfolio:
STEM College
School / Department:
STEM|Health and Biomedical Sciences
Phone:
+61399256066
Campus:
Bundoora West
Contact me about:
Research supervision
Dr Thomas Angelovich studies the mechanisms which drive inflammatory diseases in HIV-infected individuals and the elderly.
Dr Angelovich researches the mechanisms which drive inflammatory diseases (such as cardiovascular disease and dementia) in HIV-infected individuals and the elderly. By understanding this progression, Dr Angelovich aims to identify targets for therapeutic intervention and to improve health outcomes for HIV-infected individuals.
- Gartner, M.,Angelovich, T.,Flynn, J.,Churchill, M.,Gorry, P.,Roche, M., et al., . (2023). Persistence of envelopes in different CD4+T-cell subsets in antiretroviral therapy-suppressed people with HIV In: AIDS, 37, 247 - 257
- Byrnes, S.,Angelovich, T.,Cochrane, C.,Jenkins, T.,Roche, M.,Estes, J.,Churchill, M. J., et al, . (2023). Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques In: PLoS Pathogens, 19, 1 - 26
- Tumpach, C.,Cochrane, C.,Kim, Y.,Ong, J.,Angelovich, T.,Churchill, M.,Roche, M., et al, . (2023). Adaptation of the intact proviral DNA assay to a nanowell-based digital PCR platform In: Journal of Virus Eradication, 9, 1 - 6
- Cochrane, C.,Angelovich, T.,Byrnes, S.,Waring, E.,Guanizo, A.,Trollope, G.,Zhou, J.,Vue, J.,Senior, L.,Wanicek, E.,Jamal Eddine, J.,Jenkins, T.,Gorry, P.,Roche, M.,Churchill, M. J., et al, . (2022). Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART In: Annals of Neurology, 92, 532 - 544
- Byrnes, S.,Angelovich, T.,Busman-Sahay, K.,Cochrane, C.,Roche, M.,Estes, J.,Churchill, M. (2022). Non-Human Primate Models of HIV Brain Infection and Cognitive Disorders In: Viruses, 14, 1 - 20
- Aggarwal, A.,Akerman, A.,Milogiannakis, V.,Silva, M.,Angelovich, T.,Waring, E.,Churchill, M., et al, . (2022). SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern In: eBioMedicine, 84, 1 - 13
- Angelovich, T.,Churchill, M.,Wright, E.,Brew, B. (2021). New Potential Axes of HIV Neuropathogenesis With Relevance to Biomarkers and Treatment In: Current Topics in Behavioral Neurosciences, 50, 3 - 39
- Hearps, A.,Angelovich, T.,Trevillyan, J.,Wong, M.,Calmy, A.,Hoy, J.,Jaworowski, A. (2021). Effect of Rosuvastatin Therapy on Biomarkers of Inflammation and Immune Activation in People With Human Immunodeficiency Virus at Intermediate Cardiovascular Risk In: Journal of Infectious Diseases, 224, 667 - 672
- Buckley, S.,Byrnes, S.,Cochrane, C.,Roche, M.,Estes, J.,Selemidis, S.,Angelovich, T.,Churchill, M. (2021). The role of oxidative stress in HIV-associated neurocognitive disorders In: Brain, Behavior, and Immunity - Health, 13, 1 - 11
- Gartner, M.,Gorry, P.,Tumpach, C.,Zhou, J.,Dantanarayana, A.,Chang, J.,Angelovich, T.,Ellenberg, P.,Laumaea, A.,Nonyane, M.,Moore, P.,Lewin, S.,Churchill, M.,Flynn, J.,Roche, M. (2020). Longitudinal analysis of subtype C envelope tropism for memory CD4+T cell subsets over the first 3 years of untreated HIV-1 infection In: Retrovirology, 17, 1 - 15
1 Masters by Research Completions2 PhD Current Supervisions
HIV, ageing, Neuroinflammation, Cardiovascular disease
- Characterization of the intact and defective HIV reservoirs in myeloid cells in the brain. Funded by: National Institutes of Health Grant 2017 onwards from (2021 to 2024)
- Ex vivo human organotypic brain slice cultures as a powerful tool to advance NeuroHIV cure strategies. Funded by: WMIMR Australian Centre for HIV and Hepatitis Virology Research Grant (ACH4) from (2021 to 2022)
- Characterising the role of epigenetic marks in driving monocyte-derived foam cell formation associated with atherosclerosis in ageing individuals. Funded by: Rebecca L. Cooper Medical Research Foundation - Competitive from (2020 to 2023)
- Developing novel drug delivery strategies to target myeloid reservoirs of HIV in the brain. Funded by: WMIMR Australian Centre for HIV and Hepatitis Virology Research Grant (ACH4) from (2020 to 2021)
- Elucidating the mechanisms driving the pathophysiology of HIV-associated neurocognitive disorders. Funded by: NHMRC Project Grants 2018 from (2019 to 2023)