Dr Amy Gelmi takes a multidisciplinary approach to characterising the live response of stem cells on ‘smart biomaterials’, focusing on developing new approaches for individual patient stem cell therapy.
Dr. Amy Gelmi is a Vice Chancellor's Research Fellowship at RMIT University where her research explores applying external stimuli to control stem cell fate for tissue engineering. Dr Gelmi's work spans dynamic biomaterials, material design, nanoscale characterisation, and advanced fabrication.
Dr Gelmi's background began with her PhD in using atomic force microscopy for biomaterial characterisation at the Intelligent Polymer Research Institute (IPRI) at the University of Wollongong, and continued using conductive polymer biomaterials to develop electroactive scaffolds for cardiac patch tissue engineering at Linköping University, Sweden. Dr. Gelmi then moved to Imperial College London as a Horizon 2020 Marie Sklodowska-Curie Individual Fellow in the Stevens Group in the Department of Materials in 2015 where her research focused on understanding the behaviour of stem cells on dynamic biomaterials using highly sensitive real time characterisation tools.
Dr Gelmi's research builds on this further, where her group focuses on investigating intracellular changes in stem cells using advanced bio atomic force microscopy, creating custom fabricated cell culture devices, and developing an optimised approach to using external stimuli to drive targeted stem cell differentiation. This work aims to develop new approaches to personalised medicine, generating targeted tissue on an individual patient basis.
Group website: www.thegelmigroup.org
- Supervision of undergraduate research placement students, post-graduate Honours, Masters and PhD students.
- Mentor in The Professional Scientist (ONPS2335).
- Lecturer in Chemistry for Life Sciences (CHEM1239).
- SEH Academic Staff Representative on the Academic Board
- SEH Academic Staff Representative on the Research Committee
- EMCR Representative for Victoria, ASBTE
- Bachelor of Science (Nanotechnology) (First Class Honours), Curtin University, Perth, Australia, 2007
- PhD (Chemistry), University of Wollongong, Wollongong, Australia, 2013
- August Ambattu, L.,Knight, C.,Lin, K.,Gelmi, A.,Yeo, L. (2023). Calcium-dependent cAMP mediates the mechanoresponsive behaviour of endothelial cells to high-frequency nanomechanostimulation In: Biomaterials, 292, 1 - 15
- August Ambattu, L.,Gelmi, A.,Yeo, L. (2022). Short-Duration High Frequency MegaHertz-Order Nanomechanostimulation Drives Early and Persistent Osteogenic Differentiation in Mesenchymal Stem Cells In: Small, 18, 1 - 13
- Dorishetty, P.,Balu, R.,Gelmi, A.,Mata, J.,Quigley, A.,Dutta, N.,Roy Choudhury, N. (2022). Microporosity engineered printable silk/graphene hydrogels and their cytocompatibility evaluations In: Materials Today Advances, 14, 1 - 14
- Lin, Y.,Penna, M.,Spicer, C.,Gelmi, A.,Yarovsky, I., et al., . (2021). High-Throughput Peptide Derivatization toward Supramolecular Diversification in Microtiter Plates In: ACS Nano, 15, 4034 - 4044
- Gelmi, A.,Schutt, C. (2021). Stimuli-Responsive Biomaterials: Scaffolds for Stem Cell Control In: Advanced Healthcare Materials, 10, 2001125 - 2001155
- Puetzer, J.,Ma, T.,Sallen, I.,Gelmi, A.,Stevens, M. (2021). Driving Hierarchical Collagen Fiber Formation for Functional Tendon, Ligament, and Meniscus Replacement In: Biomaterials, 269, 1 - 10
- Kit-Anan, W.,Mazo, M.,Wang, B.,Gelmi, A., et al, . (2021). Multiplexing physical stimulation on single human induced pluripotent stem cell-derived cardiomyocytes for phenotype modulation In: Biofabrication, 13, 1 - 16
- Fong, J.,Harrison, M.,Rifai, M.,Fox, K.,Gelmi, A. (2021). Diamond in the Rough: Toward Improved Materials for the Bone-Implant Interface In: Advanced Healthcare Materials, 10, 1 - 10
- Dorishetty, P.,Balu, R.,Gelmi, A.,Mata, J.,Dutta, N.,Roy Choudhury, N. (2021). 3D Printable Soy/Silk Hybrid Hydrogels for Tissue Engineering Applications In: Biomacromolecules, 22, 3668 - 3678
- Tong, W.,AREGUETA ROBLES, U.,Sherrell, A. (2021). Bioelectronics and Neural Interfaces In: The Chemistry of Inorganic Biomaterials, Royal Society of Chemistry, United Kingdom
1 PhD Completions5 PhD Current Supervisions
- Dual Stimulation Approach to Stem Cell Based Tissue Engineering. Funded by: ARC Discovery Projects 2020 from (2020 to 2023)