Professor Denise Jackson
Professor
Details
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College: School of Health and Biomedical Sciences
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Department: Health and Biomedical Sciences
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Campus: Bundoora West Australia
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denise.jackson@rmit.edu.au
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ORCID: 0000-0001-9044-8009
Open to
- Masters Research or PhD student supervision
- Media enquiries
About
Professor Denise Jackson is the Head of the Thrombosis and Vascular Biology laboratory and is also an Honorary NHMRC fellow.
Educational development work:
Course coordinator of MEDS1142 Medical informatics, BUSM3220 Medical laboratory quality systems and accreditation and ONPS2153 Medical informatics and laboratory management.
Principal supervisor of research students: 12 Honours, 3 Masters and 4 PhD.
Self assessment in Haematology programmes (AIMS).
Industry Experience:
Professional and community involvement:
Reviewed project grant applications for the following funding bodies and organisations:
National Health and Medical Research Council
National Heart Foundation
Women's and Children's Hospital, Adelaide. S.A.
Fellowship Reviews, Monash University, Vic.
Wellcome Trust, UK.
National Science Foundation, USA.
NATA reviewer of Haematology / Immunohaematology laboratories
Scientific Reviewer for the following journals:
Australian Institute of Medical Science Journal
Nature
Blood
Thrombosis and Haemostasis
Journal of Immunology
Journal of Histochemistry and Cytochemistry
Journal of Leukocyte Biology
Journal of Clinical Investigation
Cell Death and Differentiation
American Journal of Respiratory Cell and Molecular Biology
Educational development work:
Course coordinator of MEDS1142 Medical informatics, BUSM3220 Medical laboratory quality systems and accreditation and ONPS2153 Medical informatics and laboratory management.
Principal supervisor of research students: 12 Honours, 3 Masters and 4 PhD.
Self assessment in Haematology programmes (AIMS).
Industry Experience:
Professional and community involvement:
Reviewed project grant applications for the following funding bodies and organisations:
National Health and Medical Research Council
National Heart Foundation
Women's and Children's Hospital, Adelaide. S.A.
Fellowship Reviews, Monash University, Vic.
Wellcome Trust, UK.
National Science Foundation, USA.
NATA reviewer of Haematology / Immunohaematology laboratories
Scientific Reviewer for the following journals:
Australian Institute of Medical Science Journal
Nature
Blood
Thrombosis and Haemostasis
Journal of Immunology
Journal of Histochemistry and Cytochemistry
Journal of Leukocyte Biology
Journal of Clinical Investigation
Cell Death and Differentiation
American Journal of Respiratory Cell and Molecular Biology
Supervisor projects
Identifying predictive biomarkers of thrombosis – the role of the fibrinolytic system
- 5 Aug 2024
- Does the new BCR-Abl Asciminib (ABL001) Tyrosine Kinase inhibitor induse platelets activation, increase thrombus formation, and promote prothromboinflammatory state?
- 18 Mar 2022
- Defining the effect of Btk inhibitors on haemostasis and thrombosis
- 15 Mar 2022
- Molecular mechanisms of immunoreceptors in platelets
- 3 Jul 2017
- Effects of Multiple Myeloma Therapy on Haemostasis and Thrombosis
- 1 Jan 2017
- Investigating the Impact of Bruton¿s Tyrosine Kinase Inhibitors used in the Treatment of Lymphoproliferative Disease on Haemostasis and Thrombosis
- 20 Jul 2015
- Differential effects of tyrosine kinase inhibitors in haemostasis, thrombosis and inflammation
- 2 Mar 2015
Teaching interests
Thrombosis, platelet biology, mouse models, human platelets, anti-platelet therapy, biochemistry, atherosclerosis, vascular biology.
Research interests
Cardiovascular Medicine and Haematology, Clinical Sciences, Pharmacology and Pharmaceutical Sciences, Oncology and Carcinogenesis, Immunology, Medical Microbiology
Research in the Thrombosis and Vascular Diseases Research team aims to understand the cellular mechanisms of how blood clots are formed and what leads to stabilisation of blood clots. The research of Associate Professor Jackson and her team ranges from work on the cellular, molecular, physiological and biochemical aspects of thrombosis, to small animal models of in vivo thrombus formation and ischaemic stroke. In addition, research of this team examines the importance of cell surface receptors known as immunoreceptors in infection and immunity, with a particular emphasis on bacterial pathogens.
Research objectives
To study mechanisms that regulate platelet thrombus formation in mouse models.
To study immunoreceptors in the immune system in our established models.
Develop a new understanding on how immunoreceptors recognise and process bacterial pathogens to regulate immunity.
To gain knowledge on the importance of tetraspanins and immunoreceptors in regulating blood clots.
To study mechanisms of signaling and compartmentalisation in platelet responsiveness.
To obtain crystal structures of immunoreceptors and use this information to design drugs.
Research in the Thrombosis and Vascular Diseases Research team aims to understand the cellular mechanisms of how blood clots are formed and what leads to stabilisation of blood clots. The research of Associate Professor Jackson and her team ranges from work on the cellular, molecular, physiological and biochemical aspects of thrombosis, to small animal models of in vivo thrombus formation and ischaemic stroke. In addition, research of this team examines the importance of cell surface receptors known as immunoreceptors in infection and immunity, with a particular emphasis on bacterial pathogens.
Research objectives
To study mechanisms that regulate platelet thrombus formation in mouse models.
To study immunoreceptors in the immune system in our established models.
Develop a new understanding on how immunoreceptors recognise and process bacterial pathogens to regulate immunity.
To gain knowledge on the importance of tetraspanins and immunoreceptors in regulating blood clots.
To study mechanisms of signaling and compartmentalisation in platelet responsiveness.
To obtain crystal structures of immunoreceptors and use this information to design drugs.
