STAFF PROFILE
Dr. Michael Roche
Position:
Visiting Research Fellow
College / Portfolio:
STEM College
Phone:
+61399257068
Email:
michael.roche@rmit.edu.au
Campus:
City Campus
Contact me about:
Research supervision
- Characterization of the intact and defective HIV reservoirs in myeloid cells in the brain. Funded by: National Institutes of Health Grant 2017 onwards from (2021 to 2024)
1 PhD Completions and 1 Masters by Research Completions1 PhD Current Supervisions
Human Immunodeficiency virus; viral entry; viral latency
- Gartner, M.,Angelovich, T.,Flynn, J.,Churchill, M.,Gorry, P.,Roche, M., et al., . (2023). Persistence of envelopes in different CD4+T-cell subsets in antiretroviral therapy-suppressed people with HIV In: AIDS, 37, 247 - 257
- Byrnes, S.,Angelovich, T.,Cochrane, C.,Jenkins, T.,Roche, M.,Estes, J.,Churchill, M. J., et al, . (2023). Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques In: PLoS Pathogens, 19, 1 - 26
- Tumpach, C.,Cochrane, C.,Kim, Y.,Ong, J.,Angelovich, T.,Churchill, M.,Roche, M., et al, . (2023). Adaptation of the intact proviral DNA assay to a nanowell-based digital PCR platform In: Journal of Virus Eradication, 9, 1 - 6
- Tumpach, C.,Rhodes, A.,Kim, Y.,Roche, M., et al, . (2023). Adaptation of Droplet Digital PCR-Based HIV Transcription Profiling to Digital PCR and Association of HIV Transcription and Total or Intact HIV DNA In: Viruses, 15, 1 - 17
- Roche, M. (2023). Venetoclax, alone and in combination with the BH3 mimetic S63845, depletes HIV-1 latently infected cells and delays rebound in humanized mice In: Cell Reports Medicine, , 1 - 1
- Uldrick, T.,Adams, S.,Fromentin, R.,Roche, M., et al, . (2022). Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy In: Science translational medicine, 14, 1 - 24
- Rawat, P.,Zerbato, J.,Rhodes, A.,Roche, M., et al, . (2022). Factors associated with weak positive SARS-CoV-2 diagnosis by reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR) In: Pathology, 54, 623 - 628
- Cochrane, C.,Angelovich, T.,Byrnes, S.,Waring, E.,Guanizo, A.,Trollope, G.,Zhou, J.,Vue, J.,Senior, L.,Wanicek, E.,Jamal Eddine, J.,Jenkins, T.,Gorry, P.,Roche, M.,Churchill, M. J., et al, . (2022). Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART In: Annals of Neurology, 92, 532 - 544
- Byrnes, S.,Angelovich, T.,Busman-Sahay, K.,Cochrane, C.,Roche, M.,Estes, J.,Churchill, M. (2022). Non-Human Primate Models of HIV Brain Infection and Cognitive Disorders In: Viruses, 14, 1 - 20
- Buckley, S.,Byrnes, S.,Cochrane, C.,Roche, M.,Estes, J.,Selemidis, S.,Angelovich, T.,Churchill, M. (2021). The role of oxidative stress in HIV-associated neurocognitive disorders In: Brain, Behavior, and Immunity - Health, 13, 1 - 11