The study compared 44 adults with untreated OSA to 44 healthy controls, assessing their recall of different types of autobiographical memories from their childhood, early adult life and recent life.
The results showed people with OSA had significantly more overgeneral memories - 52.3% compared with 18.9% of the control group.
The study also looked at recall of semantic memory (facts and concepts from your personal history, like the names of your school teachers) and episodic memory (events or episodes, like your first day of high school).
While people with OSA struggled with semantic memory, their episodic memory was preserved. This is likely related to their fragmented sleeping patterns, as research has shown that good sleep is essential for the consolidation of semantic autobiographical memory.
Across both groups, being older was associated with having a higher number of overgeneral autobiographical memories while higher depression was linked to having worse semantic memory.
Jackson, a Vice-Chancellor’s Senior Research Fellow in RMIT’s School of Biomedical and Health Sciences, said the results showed the need for further studies to better understand the role of untreated OSA on memory processing.
“Brain scans of people with sleep apnoea show they have a significant loss of grey matter from regions that overlap with the autobiographic memory network,” she said.
“We need to look at whether there’s a shared neurobiological mechanism at work – that is, does the dysfunction of that network lead to both depression and memory problems in people with sleep apnoea?”
Jackson said the use of CPAP machines to treat OSA had been shown to improve some of the cognitive impairments related to the condition.
“An important next step will be to determine whether successful treatment of sleep apnoea can also help counter some of these memory issues or even restore the memories that have been lost.”
The study - conducted with collaborators from the Institute for Breathing and Sleep, Florey Institute of Neuroscience and Mental Health, and University of Melbourne - is published in Journal of the International Neuropsychology Society (DOI:10.1017/S1355617718001091).
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About Sleep Apnoea
· Sleep apnoea occurs when the muscles in the upper airway collapse during sleep, blocking off the airway above the voice box.
· Breathing stops for a period of time (generally between 10 seconds and up to 1 minute) until the brain registers the lack of breathing or a drop in oxygen levels and sends a small wake-up call. The sleeper rouses slightly, opens the upper airway, typically snorts and gasps, then drifts back to sleep almost immediately. This pattern can repeat itself hundreds of times a night, causing fragmented sleep.
· It’s estimated that about five per cent of Australians suffer from sleep apnoea.
· Around one in four men over the age of 30 years have some degree of sleep apnoea, making it more common than asthma.
· Conservative treatment includes weight loss and cutting back on alcohol.
· Active treatment includes nasal CPAP, mouthguards or surgical correction of upper airway obstruction.
· Daytime sleepiness may distinguish simple snorers from people with sleep apnoea.
(source: BetterHealth Channel)
Story: Gosia Kaszubska