STAFF PROFILE
Professor Toby Allen
Position:
Professor
College / Portfolio:
STEM College
School / Department:
STEM|School of Science
Phone:
+61399250439
Email:
toby.allen@rmit.edu.au
Campus:
City Campus
Contact me about:
Research supervision
- Lev, B.,Chennath, M.,Cranfield, C.,Cornelius, F.,Allen, T.,Clarke, R. (2023). Involvement of the alpha-subunit N-terminus in the mechanism of the Na+,K+-ATPase In: Biochimica et Biophysica Acta - Molecular Cell Research, 1870, 1 - 9
- Fan, C.,Flood, E.,Sukomon, N.,Agarwal, S.,Allen, T.,Nimigean, C. (2023). Calcium-gated potassium channel blockade via membrane-facing fenestrations In: Nature Chemical Biology, , 1 - 28
- Chen, P.,Vorobyov, I.,Roux, B.,Allen, T. (2021). Molecular Dynamics Simulations Based on Polarizable Models Show that Ion Permeation Interconverts between Different Mechanisms as a Function of Membrane Thickness In: Journal of Physical Chemistry B, 125, 1020 - 1035
- Ngo, V.,Li, H.,MacKerell, A.,Allen, T.,Roux, B.,Noskov, S. (2021). Polarization Effects in Water-Mediated Selective Cation Transport across a Narrow Transmembrane Channel In: Journal of Chemical Theory and Computation, 17, 1726 - 1741
- Lev, B.,Allen, T. (2020). Simulating ion channel activation mechanisms using swarms of trajectories In: Journal of Computational Chemistry, 41, 387 - 401
- Lynagh, T.,Flood, E.,Boiteux, C.,Sheikh, Z.,Allen, T.,Pless, S. (2020). Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels In: The Journal of general physiology, 152, 1 - 12
- Fang, C.,Sukomon, N.,Flood, E.,Rheinberger, J.,Allen, T.,Nimigean, C. (2020). Ball-and-chain inactivation in a calcium-gated potassium channel In: Nature, 580, 288 - 293
- Boiteux, C.,Posson, D.,Allen, T.,Nimigean, C. (2020). Selectivity filter ion binding affinity determines inactivation in a potassium channel In: Proceedings of the National Academy of Sciences, 117, 29968 - 29978
- Garcia, A.,Lev, B.,Hossain, K.,Gorman, A.,Diaz, D.,Pham, T.,Cornelius, F.,Allen, T.,Clarke, R. (2019). Cholesterol depletion inhibits Na,K-ATPase activity in a near-native membrane environment In: Journal of Biological Chemistry, 294, 5956 - 5969
- Flood, E.,Boiteux, C.,Lev, B.,Vorobyov, I.,Allen, T. (2019). Atomistic Simulations of Membrane Ion Channel Conduction, Gating, and Modulation In: Chemical Reviews, 119, 7737 - 7832
Note: Supervision projects since 2004
1 PhD Completions2 PhD Current Supervisions
Computational biophysics, Statistical mechanics, Physical chemistry, Neuroscience, Bionanotechnology, Ion channels, Membranes and membrane proteins
- Unravelling the mechanisms of sodium-selectivity in biological ion channels. Funded by: ARC Discovery Projects commencing in 2022 from (2022 to 2025)
- Uncovering the molecular mechanisms of potassium channel activity. Funded by: ARC Discovery Projects 2021 from (2021 to 2024)
- The structural basis for promiscuity of drug binding to hERG K+ channels (administered by UNSW). Funded by: National Health and Medical Research Council (NHMRC) Project Grants 2017 (for funding commencing in 2018) from (2018 to 2021)
- How cholesterol optimises ion pump function in animal membranes (Administered by University of Sydney). Funded by: 010-ARC Discovery Projects 2017 from (2017 to 2019)
- A high-performance cloud resource for computational modelling - led by The University of Melbourne. Funded by: ARC Linkage Infrastructure, Equipment and Facilities (LIEF) Grant 2017 from (2017 to 2017)