STAFF PROFILE
Professor Toby Allen
Position:
Professor
College / Portfolio:
School of Science Cluster
School / Department:
Physics
Phone:
99250439
Email:
toby.allen@rmit.edu.au
Campus:
Melbourne City Campus
Contact me about:
Research supervision
- Lynagh, T.,Flood, E.,Boiteux, C.,Sheikh, Z.,Allen, T.,Pless, S. (2020). Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels In: The Journal of general physiology, 152, 1 - 12
- Boiteux, C.,Flood, E.,Allen, T. (2019). Comparison of permeation mechanisms in sodium-selective ion channels In: Neuroscience Letters, 700, 3 - 8
- Garcia, A.,Lev, B.,Hossain, K.,Gorman, A.,Diaz, D.,Pham, T.,Cornelius, F.,Allen, T.,Clarke, R. (2019). Cholesterol depletion inhibits Na,K-ATPase activity in a near-native membrane environment In: Journal of Biological Chemistry, 294, 5956 - 5969
- Flood, E.,Boiteux, C.,Lev, B.,Vorobyov, I.,Allen, T. (2019). Atomistic Simulations of Membrane Ion Channel Conduction, Gating, and Modulation In: Chemical Reviews, 119, 7737 - 7832
- Lev, B.,Allen, T. (2019). (In Press) Simulating ion channel activation mechanisms using swarms of trajectories. In: Journal of Computational Chemistry, , 1 - 15
- Flood, E.,Boiteux, C.,Allen, T. (2018). Selective ion permeation involves complexation with carboxylates and lysine in a model human sodium channel In: PLoS Computational Biology, 14, 1 - 32
- Lev, B.,Murail, S.,Poitevin, F.,Cromer, B.,Baaden, M.,Delarue, M.,Allen, T. (2017). String method solution of the gating pathways for a pentameric ligand-gated ion channel In: Proceedings of the National Academy of Sciences of the United States of America, 114, E4158 - E4167
- Lynagh, T.,Flood, E.,Boiteux, C.,Wulf, M.,Komnatnyy, V.,Colding, J.,Allen, T.,Pless, S. (2017). A selectivity filter at the intracellular end of the acid-sensing ion channel pore In: eLife, 6, 1 - 21
- Vandenberg, J.,Perozo, E.,Allen, T. (2017). Towards a structural view of drug binding to hERG K+ Channels In: Trends in Pharmacological Sciences, 38, 899 - 907
- Garcia, A.,Pratap, P.,Lupfert, C.,Cornelius, F.,Jacquemin, D.,Lev, B.,Allen, T. (2017). The voltage-sensitive dye RH421 detects a Na+,K+-ATPase conformational change at the membrane surface In: Biochimica et Biophysica Acta - Biomembranes, 1859, 813 - 823
Note: Supervision projects since 2004
1 PhD Completions1 PhD Current Supervisions
Computational biophysics, Statistical mechanics, Physical chemistry, Neuroscience, Bionanotechnology, Ion channels, Membranes and membrane proteins
- The structural basis for promiscuity of drug binding to hERG K+ channels (administered by UNSW). Funded by: National Health and Medical Research Council (NHMRC) Project Grants 2017 (for funding commencing in 2018) from (2018 to 2020)
- How cholesterol optimises ion pump function in animal membranes (Administered by University of Sydney). Funded by: 010-ARC Discovery Projects 2017 from (2017 to 2019)
- A high-performance cloud resource for computational modelling - led by The University of Melbourne. Funded by: ARC Linkage Infrastructure, Equipment and Facilities (LIEF) Grant 2017 from (2017 to 2017)
- How do anaesthetics work? A rational basis for safer general anaesthesia. Funded by: National Health and Medical Research Council (NHMRC) Project Grants 2016 from (2016 to 2019)
- Predictive multiscale in silico cardio-pharmacology (Administered by UC Davis). Funded by: National Institutes of Health Research Project Grant 2015 from (2015 to 2020)