STAFF PROFILE
Professor Melissa Churchill
Position:
Professor
College / Portfolio:
Biomedical Science Cluster
School / Department:
Human Biosciences
Phone:
+61 3 9925 6657
Campus:
Bundoora Campus
- Defining HIV reservoirs in the central nervous system. Funded by: Jack Brockhoff Foundation Medical Grant 2017 onwards from (2018 to 2020)
- Developing BASEScope: a method to detect replication competent HIV for HIV cure research. Funded by: WMIMR Australian Centre for HIV and Hepatitis Virology Research Grant (ACH2) 2018 from (2018 to 2018)
- Understanding HIV Resistance to Entry Inhibitors to Advance the Development of Novel Antivirals. Funded by: 044-National Health and Medical Research Council (NHMRC) Project Grants 2017 from (2017 to 2019)
- Viral Determinants of HIV-1 Transcriptional Latency in the Central Nervous System: Impact on Cure Strategies. Funded by: National Health and Medical Research Council (NHMRC) Project Grants 2016 from (2016 to 2019)
- HIV Phenotypes Important for the Establishment of Persistent Reservoirs in the Central Nervous System and which impact Neurotropism and Neuropathogenesis. Funded by: National Health and Medical Research Council (NHMRC) Project Grants 2016 from (2016 to 2019)
- Wang, H.,Blackall, M.,Sominsky, L.,Spencer, S.,Vlahos, R.,Churchill, M.,Bozinovski, S. (2018). Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production In: Journal of Neuroinflammation, 15, 1 - 11
- Flynn, J.,Ellenberg, P.,Duncan, R.,Ellett, A.,Zhou, J.,Sterjovski, J.,Cashin, K.,Borm, K.,Gray, L.,Lewis, M.,Jubb, B.,Westby, M.,Lee, B.,Lewin, S.,Churchill, M.,Roche, M.,Gorry, P. (2017). Analysis of clinical HIV-1 strains with resistance to maraviroc reveals strain-specific resistance mutations, variable degrees of resistance, and minimal cross-resistance to other CCR5 antagonists In: AIDS Research and Human Retroviruses, 33, 1220 - 1235
- Gray, L.,Cowley, D.,Welsh, C.,Lu, H.,Brew, B.,Lewin, S.,Wesselingh, S.,Gorry, P.,Churchill, M. (2016). CNS-specific regulatory elements in brain-derived HIV-1 strains affect responses to latency-reversing agents with implications for cure strategies In: Molecular Psychiatry, 21, 574 - 584
- Gray, L.,On, H.,Roberts, E.,Lu, H.,Moso, M.,Raison, J.,Papaioannou, C.,Cheng, W.,Ellett, A.,Jacobson, J.,Purcell, D.,Wesselingh, S.,Gorry, P.,Lewin, S.,Churchill, M. (2016). Toxicity and in vitro activity of HIV-1 latency-reversing agents in primary CNS cells In: Journal of NeuroVirology, 22, 455 - 463
- Borm, K.,Jakobsen, M.,Cashin, K.,Flynn, J.,Ellenberg, P.,Ostergaard, L.,Lee, B.,Churchill, M.,Roche, M.,Gorry, P. (2016). Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc In: Retrovirology, 13, 1 - 13
- Saleh, S.,Lu, H.,Evans, V.,Harisson, D.,Zhou, J.,Jaworowski, A.,Sallmann, G.,Cheong, K.,Mota, T.,Tennakoon, S.,Angelovich, T.,Anderson, J.,Andrew Harman, A.,Cunningham, A.,Gray, L.,Churchill, M.,Mak, J.,Drummer, H.,Vatakis, D.,Lewin, S.,Cameron, P. (2016). HIV integration and the establishment of latency in CCL19-treated resting CD4(+) T cells require activation of NF-kappa B In: Retrovirology, 13, 1 - 12
- Tomusange, K.,Wijesundara, D.,Gummow, J.,Garrod, T.,Li, Y.,Gray, L.,Churchill, M.,Grubor-Bauk, B.,Gowan, E. (2016). A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice In: Scientific Reports, 6, 1 - 10
- Gray, L.,Brew, B.,Churchill, M. (2016). Strategies to target HIV-1 in the central nervous system In: Current Opinion in HIV and AIDS, 11, 371 - 375
- Meikle, P.,Low, H.,Churchill, M.,Bukrinsky, M.,Sviridov, D. (2016). Lipidomic dataset of plasma from patients infected with wild type and nef-deficient HIV-1 strain In: Data in Brief, 6, 168 - 175
- Low, H.,Cheng, L.,Di Yacovo, M.,Churchill, M.,Meikle, P.,Bukrinsky, M.,Hill, A.,Sviridov, D. (2016). Lipid metabolism in patients infected with Nef-deficient HIV-1 strain In: Atherosclerosis, 244, 22 - 28