STAFF PROFILE
Dr. Hong Li
Dr Li is the Associate of School of Science. His research focuses on the clinical effects and mechanisms of natural products for cancers, infectious diseases and metabolic diseases through the network-based investigation which links to drug discovery.
Research interests
- Computational modelling and simulations of biomolecular systems
- Synergistic effects of compounds in natural products
- Computer-aided novel combination drug discovery
- Systematic reviews and meta-analysis on effects and safety of Chinese herbal medicine for chronic diseases
- Randomised controlled clinical trials of Chinese herbal medicine for chronic diseases
Research funding
- Supercomputer and structure-based multi-ligand molecular modeling for the synergistic effects of Danggui Beimu Kushen Wan and abiraterone in the treatment of castrate-resistant prostate cancer, funded by National Natural Science Foundation of China, from 2023 to 2025, Grant No. 8220140209, CNY 300,000;
- Supercomputing structure-based multi-ligands molecular modeling to investigate the cooperativity of Danggui Beimu Kushen Wan and abiraterone for castrate-resistant prostate cancer, funded by China Postdoctoral Science Foundation, from 2022 to 2023, Grant No.: 2022M711534, CNY 80,000;
- Supercomputing SMMM technology to explore the synergistic mechanism of Danggui Beimu Kushen Wan with abiraterone in the treatment of CRPC, funded by Guangdong Basic and Applied Basic Research Foundation, China, from 2021 to 2024, Grant No.: 2021A1515110082, CNY 100,000;
- Supercomputer virtual screening and network pharmacology of Danggui Beimu Kushen Wan on Cytochrome P450 family for prostate cancer, funded by Human Resources and Social Security Department of Guangdong Province, China, from 2021 to 2022, no grant number, CNY 100,000.
Awards
- Deputy Vice-Chancellor’s Higher Degree by Research Prize, RMIT University, 2021
Dr Li utilises supercomputers to perform computational modelling and screening to seek the synergistic effects of compounds in natural products. He also investigates the mechanisms of action of Chinese herbal formulae for cancers, infectious diseases and metabolic diseases via network pharmacological analysis.
By email.
- Doctor of Philosophy, RMIT University, Australia, 2020
- Bachelor of Medicine (Chinese Medicine), Guangzhou University of Chinese Medicine, China, 2013
Young Editorial Board Member
- Traditional Medicine Research
- Medical Data Mining
Reviewer for peer-reviewed journals
- Frontiers in Pharmacology (SCI, IF: 5.988)
- Frontiers in Nutrition (SCI, IF: 6.59)
- Frontiers in Cell and Developmental Biology (SCI, IF: 6.018)
- Frontiers in Oncology (SCI, IF: 5.738)
- Evidence-based Complementary and Alternative Medicine (SCI, IF: 2.65)
- Journal of Pharmacy and Pharmacology (SCI, IF: 4.81)
- Alternative Therapies in Health and Medicine (SCI, IF: 1.804)
- Traditional Medicine Research (ESCI)
- Cancer Advances
- Precision Medicine Research
- Medical Data Mining
- Wu, C.,Wong, A.,Chen, Q.,Yang, S.,Chen, M.,Yang, W.,Hung, A.,Li, H., et al, . (2024). Identification of inhibitors from a functional food-based plant perillae folium against hyperuricemia via metabolomics profiling, network pharmacology and all-atom molecular dynamics simulations In: Frontiers in Endocrinology, 15, 1 - 22
- Li, H.,Komori, A.,Li, M.,Chen, X.,Yang, A.,Sun, X.,Liu, Y.,Hung, A.,Zhao, X.,Zhou, L. (2023). Multi-ligand molecular docking, simulation, free energy calculations and wavelet analysis of the synergistic effects between natural compounds baicalein and cubebin for the inhibition of the main protease of SARS-CoV-2 In: Journal of Molecular Liquids, 374, 1 - 19
- Chen, Q.,Chen, X.,CHEN, X.,Li, M.,Komori, A.,Yang, A.,Hung, A.,Li, H., et al, . (2023). Computational biomedical modeling and screening for prediction of molecular mechanisms of Simiao Pill against hyperuricemia In: Journal of Molecular Liquids, 381, 1 - 15
- You, Y.,Chen, X.,Chen, X.,Li, H.,Zhou, R., et al, . (2023). Jiawei Yanghe Decoction suppresses breast cancer by regulating immune responses via JAK2/STAT3 signaling pathway In: Journal of Ethnopharmacology, 316, 1 - 19
- Chen, Q.,Chen, X.,Chen X, et al, .,Komori, A.,Hung, A.,Li, H. (2023). Structure-based multi-ligand molecular modeling to predict the synergistic effects of limonin and obacunone from Simiao pill against nitric oxide synthase 3 associated with hyperuricemia In: Precision Medicine Research, 5, 1 - 5
- Xu, J.,Li, H.,Sze, D.,Chan, V.,Yang, W. (2022). Effectiveness of qigong and tai chi in the quality of life of patients with cancer: protocol for an umbrella review In: BMJ Open, 12, 1 - 5
- Lee, S.,Hung, A.,Li, H.,Yang, A. (2022). Mechanisms of Action of a Herbal Formula Huangqi Guizhi Wuwu Tang for the Management of Post-Stroke Related Numbness and Weakness: A Computational Molecular Docking Study In: Journal of Evidence-Based Integrative Medicine, 27, 1 - 13