Leslie Yeo

Dist. Professor Leslie Yeo

Professor

Details

  • College: School of Engineering
  • Department: School of Engineering
  • Campus: City Campus Australia
  • leslie.yeo@rmit.edu.au

Open to

  • Media enquiries
  • Masters Research or PhD student supervision

About

Leslie is a scientist and engineer with a passion for the discovery and elucidation of novel physicochemical phenomena, and their translation into practical technology for real world applications.

Leslie received his PhD from Imperial College London in 2002, for which he was awarded the Dudley Newitt prize for a computational/theoretical thesis of outstanding merit. Prior to joining RMIT, he was a Mathematical Modeller at Det Norske Veritas UK and a postdoctoral research associate in the Department of Chemical & Biomolecular Engineering at the University of Notre Dame, USA, after which he commenced a faculty position at Monash University. In addition, he has also held the Australian Research Fellowship and Australian Research Council Future Fellowship from 2009 to 2017.

Leslie was the recipient of the 2007 Young Tall Poppy Science Award from the Australian Institute for Policy & Science ‘in recognition of the achievements of outstanding young researchers in the sciences including physical, biomedical, applied sciences, engineering and technology’, both the Dean’s and Vice-Chancellor’s awards for excellence in early career research at Monash University, and the Vice-Chancellor’s award for research excellence as well as the university’s award for research innovation at RMIT. His work on microfluidics has been featured widely in the media, for example, on the Australian Broadcasting Corporation’s science television program Catalyst, 3RRR and SBS radio broadcasts, and in various articles in The Economist, New Scientist and The Washington Times, in addition to being highlighted in Nature and Science.

Leslie is co-author of the book Electrokinetically Driven Microfluidics & Nanofluidics (Cambridge University Press), and the author of over 250 research publications and 45 patent applications. He is also the Editor-in-Chief of the American Institute of Physics journal Biomicrofluidics, Associate Editor of Frontiers in Bioengineering & Biotechnology, and an editorial board member of Interfacial Phenomena & Heat Transfer, Frontiers in Bioengineering & Biotechnology, Biosensors and Micro.

Industry experience
Atmospheric Dispersion Modelling (Det Norske Veritas UK)

Awards & Honours:
2023: Fellowship of the Institution of Engineering & Technology (FIET)
2021: RMIT University Science, Technology, Engineering & Medicine College Research Impact Award
2019: RMIT University Distinguished Professorship
2018: RMIT University Vice-Chancellor’s Award for Research Excellence
2016: Johnson & Johnson World Without Disease Quickfire Challenge Award
2015: RMIT University Innovation Excellence Award
2009: Monash University Vice-Chancellor’s Award for Excellence in Research by Early Career Researchers
2009: Monash University Faculty of Engineering Early Career Researcher Award
2008: Eureka Prize People’s Choice Award Finalist
2007: Young Tall Poppy Science Award
2007: Fresh Science Award
2002: Dudley Newitt Prize
2000: Society of Chemical Industry Messel Fund Bursary
1999-2001: University of London Knight Studentship in Science & Engineering
1998-2001: Overseas Research Scholarship

Research fields

  • 401210 Microfluidics and nanofluidics
  • 510301 Acoustics and acoustical devices; waves
  • 400307 Mechanobiology
  • 401807 Nanomaterials
  • 321404 Pharmaceutical delivery technologies
  • 400302 Biomaterials
  • 320602 Medical biotechnology diagnostics (incl. biosensors)

UN sustainable development goals

  • 3 Good Health and Well Being
  • 7 Affordable and Clean Energy

Academic positions

  • Lecturer/Senior Lecturer/Associate Professor
  • Monash University
  • Mechanical & Aerospace Engineering
  • Melbourne, Australia
  • 1 May 2005 – 30 Nov 2011
  • Postdoctoral Research Associate
  • University of Notre Dame
  • Chemical & Biomolecular Engineering
  • Notre Dame, United States
  • 1 Sep 2003 – 30 Apr 2005

Non-academic positions

  • Mathematical Modeller
  • Det Norske Veritas
  • Risk Management Solutions
  • London, United Kingdom
  • 1 Jan 2002 – 30 Jun 2003

Supervisor projects

  • High Frequency Acoustic Cellular Interactions
  • 25 Sep 2024
  • Acoustic Exosomal Stimulation
  • 10 Jan 2024
  • Mucosal Vaccine Delivery through MHz Frequency Vibrations
  • 20 Jul 2023
  • Towards Integrated Miniaturisation of Actuation Schemes in Lab-on-a-Chip Point-of-Care Diagnostic Devices
  • 11 May 2023
  • Investigate the combination effects of SAW and JM2 on the behaviour of tumour cells
  • 6 Apr 2023
  • Towards Integrated Miniaturisation of Actuation Schemes in Lab-on-a-Chip Point-of-Care Diagnostic Devices
  • 3 Dec 2022
  • Synthesis of 2-D nanomaterials from MOFs/COFs
  • 31 Oct 2022
  • High frequency synthesis methods of nanomaterials for energy applications
  • 18 Dec 2021
  • Acoustofluidic Diagnostic Devices
  • 19 Aug 2021
  • Bioinspired single-cation selective sub-nanochannels
  • 25 Mar 2021
  • Integration of High-Frequency Acoustics for Electrochemical Material Synthesis and Energy Storage Systems
  • 15 Dec 2020
  • Synthesis and Modulation of Electrically Conductive-MOF Towards the Design of Electrochemical Sensors with High Stability and Efficiency
  • 12 Feb 2020
  • High Frequency (MHz) Acoustic Waves for Manipulation of Metal-Organic Frameworks
  • 24 Jul 2019
  • Acoustic Synthesis and Modulation of Two-dimensional Materials
  • 19 Jun 2019
  • High Frequency Surface Reflected Bulk Wave Induced Mechanotransduction
  • 8 Jan 2019
  • High Frequency (MHz) Acoustic Excitation for Microfluidic Actuation
  • 1 Mar 2018
  • Acoustojetting: Fundamentals, Nanolitre Droplet Dispensing and Fertility Diagnosis
  • 10 May 2017
  • Surface Acoustic Wave Nebulisation for Materials Synthesis and Biological Applications
  • 7 Apr 2017
  • Rapid Dry Exfoliation Method for Tuneable Production of Molybdenum Disulphide Quantum Dots or Large Micron-Dimension Sheets
  • 22 Aug 2016
  • Surface acoustic waves (SAW) mediated crumpled polyethyleneimine-labelled graphene oxide (CGO-PEI) synthesis as nanotherapeutic delivery platform 
  • 7 Mar 2016
  • Graphene-Loaded Agarose Hydrogel for Removal and Release of Organic Compounds in Oil and Water 
  • 24 Aug 2015
  • Surface Nanodroplets Formation & Applications
  • 2 Mar 2015
  • Acoustic Manipulation of Fluids in Synthetic and Biological Porous Materials 
  • 22 Oct 2014
  • A novel microcrystallization technique using Surface Acoustic Waves (SAW)
  • 13 Oct 2014

Teaching interests

Programs:
Chemical Engineering (https://www.rmit.edu.au/study-with-us/engineering/chemical-engineering)

Supervisor interest areas:
- Engineering (chemical, mechanical, electrical/electronic, materials)
- Science (physics, chemistry, biology)
- Biotechnology
- Nanotechnology
- Pharmaceutical science

Supervisor projects:
- Acoustomicrofluidic synthesis and manipulation of bulk (e.g., (metal-organic frameworks) and 2D crystals (e.g., transition metal dichalcogenides and MXenes)
- High frequency mechanobiology for drug delivery and tissue engineering applications
- Acoustomicrofluidic technologies for point-of-care diagnostics and drug/gene delivery
- Acoustically-driven microfluidic extensional rheometry for tear and male fertility diagnostics
- Biomimetic nasal model for personalised screening of inhaled therapeutics

Research interests

Leslie's current research interests are centered around the interactions between high frequency (MHz order) sound waves and matter (fluids, two-dimensional and bulk crystals, biomolecules, cells and microorganisms). Besides uncovering and elucidating new fundamental physicochemical microscale and nanoscale phenomena arising from these nonlinear interactions, Leslie's research is focussed on exploring their use for diverse applications (e.g., microfluidics, drug delivery and nanomedicine, diagnostics and biosensing, tissue engineering and mechanobiology, and, sonochemical materials synthesis, manipulation and processing).

Research keywords
Microfluidics, Acoustics, Nanomaterials, Drug and gene delivery, Sonochemistry, Mechanobiology

Initiatives and links

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Acknowledgement of Country

RMIT University acknowledges the people of the Woi wurrung and Boon wurrung language groups of the eastern Kulin Nation on whose unceded lands we conduct the business of the University. RMIT University respectfully acknowledges their Ancestors and Elders, past and present. RMIT also acknowledges the Traditional Custodians and their Ancestors of the lands and waters across Australia where we conduct our business - Artwork 'Sentient' by Hollie Johnson, Gunaikurnai and Monero Ngarigo.