Hao Wang

Dr. Hao Wang

Research Fellow

Details

Open to

  • Masters Research or PhD student supervision

About

Dr Hao Wang is a respiratory researcher with expertise in macrophage and neutrophil biology and their roles in disease pathogenesis, particularly in severe asthma and other chronic inflammatory lung conditions, including COPD and sarcoidosis. He also investigates how early-life exposures, such as viral infections, shape immune responses and influence lifelong lung health and disease susceptibility.

 

His research integrates preclinical models with human translations, incorporating multi-omics approaches such as single-cell and bulk transcriptomics, and lipidomics to understand how environmental cues shape immune cell heterogeneity and drive pathogenic cellular subsets. He has a strong focus on monocyte-derived and interstitial macrophages, defining their roles in airway inflammation, tissue remodelling, and treatment resistance. He is also actively engaged in industry collaboration, working closely with CSL on the development of myeloid-targeted therapies.

Research fields

  • 320103 Respiratory diseases
  • 320211 Infectious diseases
  • 3204 Immunology
  • 400603 Molecular, biological, and multi-scale communications

Supervisor projects

  • Unravelling the role of the liver-lung axis during secondary bacterial pneumonia
  • 11 Jul 2024
  • Immunophenotyping tumour associated neutrophils in lung cancer
  • 1 Jan 2023
  • Developing Novel ALOX5 mRNA Nanoparticles To Treat Incurable Non-Small Cell Lung Cancer
  • 24 Feb 2022
  • Defining and Targeting Pathogenic Myeloid Populations in Novel Models of COPD
  • 6 Feb 2020

Teaching interests

Precision Medicine; Human Pathophysiology

Research interests

  • Macrophage and neutrophil biology in chronic lung diseases
  • Immune cell plasticity and airway remodelling
  • Early-life immune programming and disease susceptibility
  • Multi-omics and single-cell transcriptomics
  • Clinical translations and industry engagement
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