STAFF PROFILE
Dr Stanley Chan
Position:
Research Officer
College / Portfolio:
Biomedical Science Cluster
School / Department:
Human Biosciences
Phone:
+61 3 9925 7353
Email:
stanley.chan@rmit.edu.au
Campus:
Melbourne City Campus
Contact me about:
Research supervision
- Lau, Y.,Mustafa, M.,Choy, K.,Chan, S.,Potocnik, S.,Herbert, T.,Woodman, O. (2018). 3 ',4 '-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice In: Scientific Reports, 8, 1 - 10
- Chan, S.,Zhao, X.,Elfowiris, A.,Ratnam, C.,Herbert, T. (2017). The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells In: Biochimie, 138, 156 - 167
- Chan, S.,Lau, Y.,Miller, A.,Ku, J.,Potocnik, S.,Ye, J.,Woodman, O.,Herbert, T. (2017). Angiotensin II causes b-cell dysfunction through an er stress-induced proinflammatory response In: Endocrinology, 158, 3162 - 3173
- Cheng, Q.,Diez Beltran, V.,Chan, S.,Brown, J.,Bevington, A.,Herbert, T. (2016). System-L amino acid transporters play a key role in pancreatic beta-cell signalling and function In: Journal of Molecular Endocrinology, 56, 175 - 187
- Wang, H.,Sun, R.,Camera, D.,Zeng, X.,Jo, E.,Chan, S.,Herbert, T.,Molero - Navajas, J.,Ye, J. (2016). Endoplasmic reticulum stress up-regulates Nedd4-2 to induce autophagy In: The FASEB Journal, 30, 2549 - 2556
- Cai, G.,Dinan, T.,Barwood, J.,De Luca, S.,Soch, A.,Ziko, I.,Chan, S.,Zeng, X.,Li, S.,Molero - Navajas, J.,Spencer, S. (2015). Neonatal overfeeding attenuates acute central pro-inflammatory effects of short-term high fat diet In: Frontiers in Neuroscience, 8, 1 - 13
- Sun, R.,Wang, H.,Zeng, X.,Chan, S.,Li, S.,Jo, E.,Leung, S.,Molero, J.,Ye, J. (2015). IRE1 impairs insulin signaling transduction of fructose-fed mice via JNK independent of excess lipid In: Biochimica et Biophysica Acta - Molecular Basis of Disease, 1852, 156 - 165
- Chan, S.,Zeng, X.,Sun, R.,Jo, E.,Zhou, X.,Wang, H.,Li, S.,Xu, A.,Watt, M.,Ye, J. (2015). Fenofibrate insulates diacylglycerol in lipid droplet/ER and preserves insulin signaling transduction in the liver of high fat fed mice In: Biochimica et Biophysica Acta - Molecular Basis of Disease, 1852, 1511 - 1519
- Areta, J.,Hawley, J.,Ye, J.,Chan, S.,Coffey, V. (2014). Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells In: Nutrition Research, 34, 1000 - 10007
- Chan, S.,Ye, J. (2013). Strategies for the discovery and development of anti-diabetic drugs from the natural products of traditional medicines In: Journal of Pharmacy and Pharmaceutical Sciences, 16, 207 - 216
- Pathways to Diabetes Prevention. Administered by Garvan Institute of Medical Research.. Funded by: National Health and Medical Research Council (NHMRC) Project Grant Pre-2014 from (2010 to 2013)
- Investigation of novel triterpenoids as new potent AMPK activators for the treatment of insulin resistant states.. Funded by: National Health and Medical Research Council (NHMRC) Project Grant Pre-2014 from (2010 to 2012)
Note: Supervision projects since 2004
1 PhD Completions
The pathogenesis of obesity and insulin resistance. Using advanced molecular biology approaches to understand cellular mechanisms and molecular changes in relation to insulin resistance for the identification of new drug targets.