STAFF PROFILE
Dr Stanley Chan
Position:
Research Officer
College / Portfolio:
Biomedical Science Cluster
School / Department:
Human Biosciences
Phone:
+61 3 9925 7353
Email:
stanley.chan@rmit.edu.au
Campus:
Melbourne City Campus
Contact me about:
Research supervision
- Cheng, Q.,Diez Beltran, V.,Chan, S.,Brown, J.,Bevington, A.,Herbert, T. (2016). System-L amino acid transporters play a key role in pancreatic beta-cell signalling and function In: Journal of Molecular Endocrinology, 56, 175 - 187
- Wang, H.,Sun, R.,Camera, D.,Zeng, X.,Jo, E.,Chan, S.,Herbert, T.,Molero - Navajas, J.,Ye, J. (2016). Endoplasmic reticulum stress up-regulates Nedd4-2 to induce autophagy In: The FASEB Journal, 30, 2549 - 2556
- Sun, R.,Wang, H.,Zeng, X.,Chan, S.,Li, S.,Jo, E.,Leung, S.,Molero, J.,Ye, J. (2015). IRE1 impairs insulin signaling transduction of fructose-fed mice via JNK independent of excess lipid In: Biochimica et Biophysica Acta - Molecular Basis of Disease, 1852, 156 - 165
- Chan, S.,Zeng, X.,Sun, R.,Jo, E.,Zhou, X.,Wang, H.,Li, S.,Xu, A.,Watt, M.,Ye, J. (2015). Fenofibrate insulates diacylglycerol in lipid droplet/ER and preserves insulin signaling transduction in the liver of high fat fed mice In: Biochimica et Biophysica Acta - Molecular Basis of Disease, 1852, 1511 - 1519
- Areta, J.,Hawley, J.,Ye, J.,Chan, S.,Coffey, V. (2014). Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells In: Nutrition Research, 34, 1000 - 10007
- Chan, S.,Sun, R.,Zeng, X.,Zi-Heng, C.,Wang, H.,Watt, M.,Ye, J. (2013). Activation of PPARa ameliorates hepatic insulin resistance and steatosis in high fructose-fed mice despite increased ER stress In: Diabetes, 62, 2095 - 2105
- Chan, S.,Ye, J. (2013). Strategies for the discovery and development of anti-diabetic drugs from the natural products of traditional medicines In: Journal of Pharmacy and Pharmaceutical Sciences, 16, 207 - 216
- Lu-Ping, R.,Chan, S.,Zeng, X.,Laybutt, R.,Iseli, T.,Sun, R.,Kraegen, E.,Cooney, G.,Turner, N.,Ye, J. (2012). Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance In: PLoS ONE, 7, e30816-1 - e30816-11
- Zeng, X.,Zhou, X.,Xu, J.,Chan, S.,Xue, C.,Molero - Navajas, J.,Ye, J. (2012). Screening for the efficacy on lipid accumulation in 3T3-L1 cells is an effective tool for the identification of new anti-diabetic compounds In: Biochemical Pharmacology, 84, 830 - 837
- Whitham, M.,Chan, S.,Pal, M.,Matthews, V.,Prelovsek, O.,Lunke, S.,El-Osta, A.,Broenneke, H.,Alber, J.,Bruning, J.,Wunderlich, T.,Lancaster, G.,Febbraio, M. (2012). Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1 In: Journal of Biological Chemistry, 287, 10771 - 10779
- Pathways to Diabetes Prevention. Administered by Garvan Institute of Medical Research.. Funded by: National Health and Medical Research Council (NHMRC) Project Grant Pre-2014 from (2010 to 2013)
- Investigation of novel triterpenoids as new potent AMPK activators for the treatment of insulin resistant states.. Funded by: National Health and Medical Research Council (NHMRC) Project Grant Pre-2014 from (2010 to 2012)
Note: Supervision projects since 2004
1 PhD Completions
The pathogenesis of obesity and insulin resistance. Using advanced molecular biology approaches to understand cellular mechanisms and molecular changes in relation to insulin resistance for the identification of new drug targets.