STAFF PROFILE
Dr. Jessica Holien
Position:
Senior Research Fellow
College / Portfolio:
STEM College
School / Department:
STEM|School of Science
Phone:
+61399257256
Email:
jessica.holien@rmit.edu.au
Campus:
Bundoora West
Contact me about:
Research supervision
- Williams, N.,Rodrigues, C.,Truong, J.,Ascher, D.,Holien, J. (2023). DockNet: high-throughput protein-protein interface contact prediction In: Bioinformatics (Oxford, England), 39, 1 - 3
- Kalkhoran, S.,Kriston-Vizi, J.,Hernandez-Resendiz, S.,Holien, J., et al, . (2022). Hydralazine protects the heart against acute ischemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission In: Cardiovascular Research, 118, 282 - 294
- Hodson, C.,Low, J.,van Twest, S.,Holien, J., et al, . (2022). Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability In: Proceedings of the National Academy of Sciences of the United States of America, 119, 1 - 12
- Niaz, A.,Truong, J.,Manoleras, A.,Fox, L.,Holien, J., et al, . (2022). Functional interaction between compound heterozygous TERT mutations causes severe telomere biology disorder In: Blood Advances, 6, 3779 - 3791
- Sarkar, S.,Soni, S.,Holien, J.,Sarkar, D., et al, . (2022). Detection of a target protein (GroEl2) in Mycobacterium tuberculosis using a derivative of 1,2,4-triazolethiols In: Molecular Diversity, 26, 2535 - 2548
- Cody, V.,Truong, J.,Holdsworth, B.,Holien, J.,Richardson, S.,Chalmers, D.,Craik, D. (2022). Structural Analysis of the Complex of Human Transthyretin with 3',5'-Dichlorophenylanthranilic Acid at 1.5 Å Resolution In: Molecules, 27, 1 - 11
- Deng, Y.,Ngo, D.,Holien, J.,Lees, J.,Lim, S. (2022). Mitochondrial Dynamin-Related Protein Drp1: a New Player in Cardio-oncology In: Current Oncology Reports, 24, 1751 - 1763
- Moody, R.,Wilson, K.,Boer, J.,Holien, J.,Flanagan, K.,Jaworowski, A.,Plebanski, M. (2021). Predicted B cell epitopes highlight the potential for COVID-19 to drive self-reactive immunity In: Frontiers in Bioinformatics, 1, 1 - 21
- Truong, J.,George, A.,Holien, J. (2021). Analysis of physicochemical properties of protein–protein interaction modulators suggests stronger alignment with the “rule of five” In: RSC Medicinal Chemistry, 12, 1731 - 1749
- Christoff, R.,Soares da Costa, T.,Bayat, S.,Holien, J.,Perugini, M.,Abbott, B. (2021). Synthesis and Structure-Activity Relationship Studies of 2, 4-Thiazolidinediones and Analogous Heterocycles as Inhibitors of Dihydrodipicolinate Synthase In: Bioorganic & Medicinal Chemistry, 52, 1 - 10
- Targeting HOXA1-expressing stem cells to improve therapies for myelodysplastic syndromes (Administered by St Vincent’s Institute of Medical Research). Funded by: NHMRC-Ideas Grants from (2022 to 2025)
- Reducing tumour incidence in adolescents with germ-line mutations in RECQL4 (Administered by St Vincents Hospital). Funded by: MRFF - 2021 Childhood Cancer Research from (2021 to 2024)
- Testing therapies in mucinous ovarian cancer in novel patient-derived models (Administered by The University of Melbourne). Funded by: US Army Medical Research and Material Command - Competitive Funding 2021 from (2021 to 2023)
- Identification of a molecule to enhance myelin repair. Funded by: CASS Foundation - grant from (2021 to 2023)
- Career recovery grants: Jessica Holien. Funded by: Veski - Inspiring Women Career Recovery Grants from (2021 to 2022)
5 PhD Current Supervisions and 1 Masters by Research Current Supervisions