STAFF PROFILE
Dr. Jessica Holien
Position:
Research Fellow
College / Portfolio:
STEM College
School / Department:
STEM|School of Science
Phone:
+61399257256
Email:
jessica.holien@rmit.edu.au
Campus:
Bundoora West
Contact me about:
Research supervision
- Hodson, C.,Low, J.,van Twest, S.,Holien, J., et al, . (2022). Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability In: Proceedings of the National Academy of Sciences of the United States of America, 119, 1 - 12
- Niaz, A.,Truong, J.,Manoleras, A.,Fox, L.,Holien, J., et al, . (2022). Functional interaction between compound heterozygous TERT mutations causes severe telomere biology disorder In: Blood Advances, 6, 3779 - 3791
- Cheung, B.,Kleynhans, A.,Mittra R etal, .,Holien, J., et al, . (2021). A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma In: Oncogene, 40, 2367 - 2381
- Kalkhoran, S.,Kriston-Vizi, J.,Hernandez-Resendiz, S.,Holien, J., et al, . (2021). Hydralazine protects the heart against acute ischemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission In: Cardiovascular Research, 118, 282 - 294
- Perry, T.,Chen, W.,Ghazali, R.,Holien, J. (2021). Role of nicotinic acetylcholine receptor subunits in the mode of action of neonicotinoid, sulfoximine and spinosyn insecticides in Drosophila melanogaster In: Insect Biochemistry and Molecular Biology, 131, 1 - 11
- Siegel, P.,Bojti, I.,Bassler, N.,Holien, J., et al, . (2021). A DARPin targeting activated Mac-1 is a novel diagnostic tool and potential anti-inflammatory agent in myocarditis, sepsis and myocardial infarction In: Basic Research in Cardiology, 116, 1 - 24
- Moody, R.,Wilson, K.,Boer, J.,Holien, J.,Flanagan, K.,Jaworowski, A.,Plebanski, M. (2021). Predicted B cell epitopes highlight the potential for COVID-19 to drive self-reactive immunity In: Frontiers in Bioinformatics, 1, 1 - 21
- Truong, J.,George, A.,Holien, J. (2021). Analysis of physicochemical properties of protein–protein interaction modulators suggests stronger alignment with the “rule of five” In: RSC Medicinal Chemistry, 12, 1731 - 1749
- Christoff, R.,Soares da Costa, T.,Bayat, S.,Holien, J.,Perugini, M.,Abbott, B. (2021). Synthesis and Structure-Activity Relationship Studies of 2, 4-Thiazolidinediones and Analogous Heterocycles as Inhibitors of Dihydrodipicolinate Synthase In: Bioorganic & Medicinal Chemistry, 52, 1 - 10
- Fatima, A.,Holien, J.,Tiwari, C.,Parker, M.,Rodgers, R.,Martin, L. (2020). Sequence comparisons of cytochrome P450 aromatases from Australian animals predict differences in enzymatic activity and/or efficiency In: Biology of Reproduction, 102, 1261 - 1269
- Targeting HOXA1-expressing stem cells to improve therapies for myelodysplastic syndromes (Administered by St Vincent’s Institute of Medical Research). Funded by: National Health and Medical Research Council Ideas Grants from (2022 to 2025)
- Reducing tumour incidence in adolescents with germ-line mutations in RECQL4 (Administered by St Vincents Hospital). Funded by: MRFF - 2021 Childhood Cancer Research from (2021 to 2024)
- Testing therapies in mucinous ovarian cancer in novel patient-derived models (Administered by The University of Melbourne). Funded by: US Army Medical Research and Material Command - Competitive Funding 2021 from (2021 to 2023)
- Career recovery grants: Jessica Holien. Funded by: Veski - Inspiring Women Career Recovery Grants from (2021 to 2022)
- Identification of a molecule to enhance myelin repair. Funded by: CASS Foundation - grant from (2021 to 2022)
4 PhD Current Supervisions and 1 Masters by Research Current Supervisions