STAFF PROFILE
Dr Andrew Hung
Position:
Senior Lecturer
College / Portfolio:
STEM College
School / Department:
STEM|School of Science
Phone:
+61399251974
Email:
andrew.hung@rmit.edu.au
Campus:
City Campus
Contact me about:
Research supervision
Research Interests
Computational modelling and simulations of biomolecular systems, with special focus on:
- Biological membranes
- Protein-lipid interactions
- Protein misfolding, abnormal aggregation and subsequent amyloid fibril formation
- Protein-surface interactions in nanobiotechnology
Current and Recent Research Projects
- Nervous system membrane proteins and receptors
- Protein and peptide interactions with biomembranes
- Nanoparticle interactions with proteins and biomembranes
- Molecular mechanisms of abnormal protein aggregation
Professional Affiliations
- Member of the Biophysical Society
- Member of the Golden Key International Honour Society
Awards
- Thomas Young Centre Junior Research Fellowship, Imperial College, London, U.K. (2008)
- Australian Postgraduate Award Scholarship, 1999
- Prize for Materials Research in Bachelor of Applied Science (Honours), RMIT University, 1998
- Dean’s List, RMIT University, Faculty of Applied Science, RMIT University, 1995-1998
- Prize for academic achievements in 3rd year Applied Chemistry, RMIT University, 1997
- Society of Chemical Industry of Victoria Student Prize, RMIT University, 1996
- Crown Scientific Award for academic achievement in 2nd year analytical chemistry, RMIT University 1996
- Baron Rubber Award for academic achievements in 2nd year Applied Chemistry, RMIT University, 1996
- Oxford Press Book Prize for academic achievements in 1st year Applied Chemistry, RMIT University, 1995
- Member of
- Postgraduate student supervisor
- BIOL2119 Computational Biology course coordinator
- ONPS2149 Introduction to Nanotechnology course coordinator
- ONPS2186 3rd year physics project coordinator
- ONPS2155 Nanotechnology Practise lecturer
- PHYS2082 lecturer
- PhD (Applied Physics), RMIT University, 2002
- Project title: Ab Initio Investigation of Pyrite FeS2 Bulk, Surfaces and Flotation Collector Adsorption
- Bachelor of Applied Science (Applied Chemistry) (Honours), RMIT University, 1998
- Bachelor of Applied Science (Applied Chemistry), RMIT University, 1997
- Condict, L.,Cavallo, J.,Hung, A.,Ashton, J.,Kasapis, S. (2023). MALDI-TOF-MS and in-depth dynamic simulations on the molecular forces determining the stability of the 4-hydroxybenzoic acid – ß-Casein complex following UHT-like treatment In: Food Chemistry, 400, 1 - 9
- Abdollahi, K.,Condict, L.,Hung, A.,Kasapis, S. (2023). Examination of ß-lactoglobulin-ferulic acid complexation at elevated temperature using biochemical spectroscopy, proteomics and molecular dynamics In: Food Hydrocolloids, 134, 1 - 9
- Aburachid Cardoso, P.,Appiah Danso, S.,Hung, A.,Dekiwadia, C.,Pradhan, N.,Strachan, J.,McDonald, B.,Firipis, K.,White, J.,Aburto Medina, A.,Conn, C.,Valery, C. (2023). Rational design of potent ultrashort antimicrobial peptides with programmable assembly into nanostructured hydrogels In: Frontiers in Chemistry, , 1 - 17
- Li, H.,Komori, A.,Li, M.,Chen, X.,Yang, W.,Sun, X.,Liu, Y.,Hung, A.,Zhao, X.,Zhou, L. (2023). Multi-ligand molecular docking, simulation, free energy calculations and wavelet analysis of the synergistic effects between natural compounds baicalein and cubebin for the inhibition of the main protease of SARS-CoV-2 In: Journal of Molecular Liquids, 374, 1 - 19
- Liang, J.,Pitsillou, E.,Ververis, K.,Guallar, V.,Hung, A.,Karagiannis, T. (2022). Small molecule interactions with the SARS-CoV-2 main protease: In silico all-atom microsecond MD simulations, PELE Monte Carlo simulations, and determination of in vitro activity inhibition In: Journal of Molecular Graphics and Modelling, 110, 1 - 9
- Pitsillou, E.,Liang, J.,Hung, A.,Karagiannis, T. (2022). The SARS-CoV-2 helicase as a target for antiviral therapy: Identification of potential small molecule inhibitors by in silico modelling In: Journal of Molecular Graphics and Modelling, 114, 1 - 11
- Lever, J.,Kreuder, F.,Henry, J.,Hung, A.,Allard, P.,Brkljaca, R.,Rix, C.,Taki, A.,Gasser, R.,Kaslin, J.,Wlodkowic, D.,Wolfender, J.,Urban, S. (2022). Targeted Isolation of Antibiotic Brominated Alkaloids from the Marine Sponge Pseudoceratina durissima Using Virtual Screening and Molecular Networking In: Marine Drugs, 20, 1 - 31
- Pitsillou, E.,Liang, J.,Beh, R.,Hung, A.,Karagiannis, T. (2022). Molecular dynamics simulations highlight the altered binding landscape at the spike-ACE2 interface between the Delta and Omicron variants compared to the SARS-CoV-2 original strain In: Computers in Biology and Medicine, 149, 1 - 12
- Lee, S.,Hung, A.,Li, H.,Yang, A. (2022). Mechanisms of Action of a Herbal Formula Huangqi Guizhi Wuwu Tang for the Management of Post-Stroke Related Numbness and Weakness: A Computational Molecular Docking Study In: Journal of Evidence-Based Integrative Medicine, 27, 1 - 13
- Darmawan, K.,Karagiannis, T.,Hughes, J.,Small, D.,Hung, A. (2022). Molecular modeling of lactoferrin for food and nutraceutical applications: insights from in silico techniques In: Critical Reviews in Food Science and Nutrition, , 1 - 24
Note: Supervision projects since 2004
13 PhD Completions and 3 Masters by Research Completions7 PhD Current Supervisions
- Nicotinic receptor structure and function probed with conotoxins. Administered by The University of Wollongong.. Funded by: ARC Discovery Projects 2015 from (2015 to 2019)
- Computational Studies of Drug, Peptide and Nanoparticle Interactions with Biological Membranes. Funded by: Victorian Partnership for Advanced Computing (VPAC) Contract from (2007 to 2008)